Rotavirus Enterotoxin NSP4 Binds to the Extracellular Matrix Proteins Laminin- 3 and Fibronectin
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چکیده
Rotavirus Enterotoxin NSP4 Binds to the Extracellular Matrix Proteins Laminin3 and Fibronectin J. A. Boshuizen, J. W. A. Rossen, C. K. Sitaram, F. F. P. Kimenai, Y. Simons-Oosterhuis, C. Laffeber, H. A. Büller, and A. W. C. Einerhand* Laboratory of Pediatrics, Pediatric Gastroenterology & Nutrition, Erasmus MC/Sophia Children’s Hospital, Rotterdam, and Eijkman-Winkler Institute, Department of Virology, University Medical Center, Utrecht, The Netherlands
منابع مشابه
Rotavirus enterotoxin NSP4 binds to the extracellular matrix proteins laminin-beta3 and fibronectin.
Rotavirus is the most important cause of viral gastroenteritis and dehydrating diarrhea in young children. Rotavirus nonstructural protein 4 (NSP4) is an enterotoxin that was identified as an important agent in symptomatic rotavirus infection. To identify cellular proteins that interact with NSP4, a two-hybrid technique with Saccharomyces cerevisiae was used. NSP4 cDNA, derived from the human r...
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